
Antioxidant BHT 264
CAS:128-37-0
Purity:99%
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Quality products make an important contribution to long-term revenue and profitability. Top Quality Chinese Manufacturer supply 23828-92-4 Ambroxol hydrochloride
Ambroxol Hydrochloride is a bronchosecretolytic drug. It is indicated as “secretolytic therapy in bronchopulmonary diseases associated with abnormal mucus secretion and impaired mucus transport. It promotes mucus clearance, facilitates expectoration and eases productive cough, allowing patients to breathe freely and deeply.
Ambroxol hydrochloride is a medication indicated to alleviate chest congestion associated with conditions that include bronchitis, pneumonia, bronchospasm asthma, cough, and allergy. Preclinically, ambroxol, the active ingredient of Mucosolvan, has been shown to increase respiratory tract secretion. It enhances pulmonary surfactant production and stimulates ciliary activity.
ambroxol
ambroxol hydrochloride
Conditions | Yield |
---|---|
With
hydrogenchloride;
In
methanol;
for 1h;
pH=Ca. 1;
Concentration;
|
97% |
With
hydrogenchloride;
In
water; acetone;
at 0 ℃;
for 1h;
Solvent;
Temperature;
|
97% |
With
hydrogenchloride;
In
ethyl acetate;
for 0.5h;
|
86% |
trans-4-[(2-amino-3,5-dibromobenzylidene)amino]cyclohexanol
ambroxol hydrochloride
Conditions | Yield |
---|---|
trans-4-[(2-amino-3,5-dibromobenzylidene)amino]cyclohexanol;
With
methanol; formic acid; 5%-palladium/activated carbon;
at 40 ℃;
for 5h;
Inert atmosphere;
Green chemistry;
With
hydrogenchloride;
In
ethanol; water;
at 20 ℃;
for 2.5h;
Reagent/catalyst;
Solvent;
Green chemistry;
|
95% |
trans-4-[(2-amino-3,5-dibromobenzylidene)amino]cyclohexanol;
With
sodium tetrahydroborate;
In
ethylene glycol;
at 20 ℃;
for 7h;
With
hydrogenchloride;
In
ethylene glycol; acetone;
at 20 ℃;
for 2h;
|
|
trans-4-[(2-amino-3,5-dibromobenzylidene)amino]cyclohexanol;
With
sodium tetrahydroborate;
In
ethanol;
at 25 ℃;
With
hydrogenchloride;
In
1,4-dioxane;
at 25 ℃;
|
> 98 % de |
The CAS number of Ambroxol hydrochloride is 23828-92-4.
More information of Ambroxol hydrochloride 23828-92-4 are:
CAS Number |
23828-92-4 |
Density |
1.612 g/cm3 |
Melting Point |
233-234.5 °C |
Boiling Point |
468.6 °C at 760 mmHg |
Flash Point |
237.2 °C |
Vapor Pressure |
1.61E-10mmHg at 25°C |
HS CODE |
29221980 |
PSA |
58.28000 |
LogP |
4.96100 |
Synonyms for Ambroxol hydrochloride 23828-92-4:Hustless (TN);trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol hydrochloride;(2-amino-3,5-dibromo-phenyl)methyl-(4-hydroxycyclohexyl)azanium;18683-91-5;Ambroxol lozenge;Ambroxol Hcl;Altretamine;Mucoangin;Hustless;Mucolear;
The chemical formula of Ambroxol hydrochloride is C13H19Br2ClN2O which containing 13 Carbon atoms,19 Hydrogen atoms,2 Bromine atoms,1 Chlorine atoms,2 Nitrogen atoms and 1 Oxygen atoms,and the molecular weight of Ambroxol hydrochloride is 414.568.
Ambroxol hydrochloride is an aromatic amine and a metabolite of bromhexine, characterized by its white crystalline powder form. It is known for its ability to stimulate mucociliary action and clear air passages in the respiratory tract, making it a valuable compound in the pharmaceutical industry.
InChI:InChI=1/C13H18Br2N2O.ClH/c14-9-5-8(13(16)12(15)6-9)7-17-10-1-3-11(18)4-2-10;/h5-6,10-11,17-18H,1-4,7,16H2;1H/t10-,11-;
Relevant articles related to Ambroxol hydrochloride:
Article |
Source |
Synthetic method of ambroxol hydrochloride |
- Paragraph 0083-0094, (2021/02/10) |
Preparation method of ambroxol hydrochloride |
- , (2020/05/14) |
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