Polyether Polyol 330N

  • CAS:9003-11-6
  • MF:
  • Purity:99%
  • Molecular Weight:
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Product Details

  • CAS: 9003-11-6
  • Appearance: yellow liquid
  • Buy High Grade Wholesale Polyether Polyol 9003-11-6 with Lowest Price

    • Molecular Formula:HO.(C2H4O)m.(C3H6O)n.H
    • Molecular Weight:102.13200
    • Appearance/Colour:White crystalline powder 
    • Vapor Pressure:<0.3 mm Hg ( 20 °C) 
    • Melting Point:57-61 °C 
    • Refractive Index:n20/D 1.466  
    • Boiling Point:32.9 °C at 760 mmHg 
    • Flash Point:55.2 °C 
    • PSA:25.06000 
    • Density:1.095 g/mL at 25 °C 
    • LogP:0.42170 

    Polyether Polyol (Cas 9003-11-6) Usage

    Chemical Properties

    Polyether Polyol generally occur as white, waxy, free-flowing prilled granules, or as cast solids. They are practically odorless and tasteless. At room temperature, poloxamer 124 occurs as a colorless liquid.


    Polykol ,Upjohn, US ,1958


    Polyether Polyol is a liquid surfactant polymer.

    Production Methods

    Poloxamer polymers are prepared by reacting propylene oxide with propylene glycol to form polyoxypropylene glycol. Ethylene oxide is then added to form the block copolymer.

    Brand name

    Lutrol F (BASF); Pluracare (BASF); Pluronic (BASF).

    Therapeutic Function

    Pharmaceutic aid (surfactant)

    General Description

    Pluronic? L-81 is a lipoprotein secretion inhibitor.

    Pharmaceutical Applications

    Polyether Polyol is nonionic polyoxyethylene–polyoxypropylene copolymers used primarily in pharmaceutical formulations as emulsifying or solubilizing agents.The polyoxyethylene segment is hydrophilic while the polyoxypropylene segment is hydrophobic. All of the Polyethylene-polypropylene glycol is chemically similar in composition, differing only in the relative amounts of propylene and ethylene oxides added during manufacture. Their physical and surface-active properties vary over a wide range and a number of different types are commercially available; Polyethylene-polypropylene glycol is used as emulsifying agents in intravenous fat emulsions, and as solubilizing and stabilizing agents to maintain the clarity of elixirs and syrups. Polyethylene-polypropylene glycol may also be used as wetting agents; in ointments, suppository bases, and gels; and as tablet binders and coatings. Poloxamer 188 has also been used as an emulsifying agent for fluorocarbons used as artificial blood substitutes, and in the preparation of solid-dispersion systems. More recently,Polyethylene-polypropylene glycol has found use in drug-delivery systems. Therapeutically, poloxamer 188 is administered orally as a wetting agent and stool lubricant in the treatment of constipation; it is usually used in combination with a laxative such as danthron. Polyethylene-polypropylene glycol may also be used therapeutically as wetting agents in eye-drop formulations, in the treatment of kidney stones, and as skin-wound cleansers. Poloxamer 338 and 407 are used in solutions for contact lens care.

    Safety Profile

    When heated to decomposition it emits acrid smoke and irritating fumes.


    Polyethylene-polypropylene glycol is stable materials. Aqueous solutions are stable in the presence of acids, alkalis, and metal ions. However, aqueous solutions support mold growth. The bulk material should be stored in a well-closed container in a cool, dry place.


    Depending on the relative concentrations, poloxamer 188 is incompatible with phenols and parabens.

    Regulatory Status

    Included in the FDA Inactive Ingredients Database (IV injections; inhalations, ophthalmic preparations; oral powders, solutions, suspensions, and syrups; topical preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.


    Antioxidant BHT 264



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